Only 16 teams remain in the 2026 NCAA Tournament, and there was a little shake up in the odds to win the national title on Sunday during the Round of 32.
The biggest upset of the weekend came when the No. 9 Iowa Hawkeyes knocked off the defending champion Florida Gators on a late 3-pointers from Alvaro Folgueiras. Florida entered the Round of 32 at +750 to win the national championship for the second year in a row, so several teams have moved up in the latest odds.
The Houston Cougars (now +750) and Illinois Fighting Illini (now +1500) face off in the Sweet 16 in the South Region, but they are the clear favorites to eventually advance to the Final Four. Nebraska (+6000) is favored over Iowa (+10000) in the other Sweet 16 matchup in that section of the bracket.
Florida’s loss wasn’t the only one that moved the odds to win the national title, and the Michigan Wolverines (+300) remain small favorites after jumping ahead of Duke (+420) and Arizona (+330) with their dominant second-round win over Saint Louis.
Here’s a look at the complete odds to win the NCAA Tournament ahead of Thursday’s Sweet 16 action.
Latest Odds to Win 2026 NCAA Tournament
Odds via FanDuel Sportsbook
- Michigan: +300
- Arizona: +330
- Duke: +420
- Houston: +750
- Purdue: +1500
- Illinois: +1500
- Iowa State: +1700
- Connecticut: +2700
- Michigan State: +3000
- St. John’s: +3300
- Arkansas: +4500
- Tennessee: +5500
- Nebraska: +6000
- Alabama: +10000
- Iowa: +10000
- Texas: +20000
Michigan, Arizona and Duke all moved up in the odds after Florida’s loss, as the Wolverines went from +310 to +300 while both Arizona (+400 to +330) and Duke (+450 to +420) saw more dramatic moves after advancing on Sunday.
Duke still has a tough path in the East Region, as UConn, Michigan State and St. John’s are all formidable teams that could win March Madness. St. John’s — Duke’s opponent in the Sweet 16 — has the worst odds of that group at +3300.
Through the first two rounds, three No. 1 seeds, four No. 2 seeds and No. 3 seeds advanced. There are only two teams that advanced that didn’t enter the tournament as top-eight seeds — No. 9 Iowa and No. 11 Texas.